EYA2

Across TCGA patient cohorts, EYA2 protein abundance is significantly associated with the RNA expression of many other genes, with 2,759 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EYA2-associated genes across cancer lineages are MIR3616, GAPDHP54, and CBY1. Each is linked with EYA2 in more than 3 cancer types. Because this analysis shows association rather than direction, both EYA2-to-partner and partner-to-EYA2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EYA2 versus MIR3616 in GBM, with a Pearson correlation of 0.65.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EYA2→partner) and Y-score (partner→EYA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	MIR3616 →	+1.886	+1.210	<.001	<.001	3	4
UCEC	GAPDHP54 →	+1.267	+0.802	<.001	<.001	3	3
UCEC	CBY1 →	+0.454	+0.593	<.001	<.001	3	2
OV	FZD3 →	+1.064	+1.268	.006	<.001	3	2
UCEC	MLPH →	+1.363	+0.645	<.001	<.001	3	2
OV	TEX11 →	-0.377	-1.081	.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,759 associations by consensus.

EYA2 vs MIR3616 — GBM

Explore this scatter interactively →