EXTL3-AS1

Across TCGA patient cohorts, EXTL3-AS1 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,547 significant associations in total. GBM shows the largest number of these associations.

The most reproducible EXTL3-AS1-associated proteins across cancer lineages are CCAR2, PLCG2, and IRF4. Each is linked with EXTL3-AS1 in more than 5 cancer types. Because this analysis shows association rather than direction, both EXTL3-AS1-to-partner and partner-to-EXTL3-AS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EXTL3-AS1 versus CCAR2 in GBM, with a Pearson correlation of 0.49.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EXTL3-AS1→partner) and Y-score (partner→EXTL3-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CCAR2 →	+0.346	+0.796	<.001	<.001	3	6
BRCA	PLCG2 →	-0.404	-0.462	<.001	<.001	3	4
BRCA	IRF4 →	-0.818	-0.674	<.001	<.001	3	4
BRCA	CTSL →	-0.454	-0.562	<.001	<.001	3	4
COAD	ZZEF1 →	-0.145	-0.241	.003	.009	3	3
LSCC	CCAR2_S678 →	+0.468	+0.267	.008	.008	2	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,547 associations by consensus.

EXTL3-AS1 vs CCAR2 — GBM

Explore this scatter interactively →