EXTL3-AS1

Across TCGA pan-cancer cohorts, EXTL3-AS1 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated EXTL3-AS1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher EXTL3-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated EXTL3-AS1 expression acts as an unfavorable survival marker, although some lineages such as BLCA and OV show a favorable association.

KIRC, BLCA, and OV are the cancer types where EXTL3-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Median	All	0.518	0.712	<.001	105	view →
BLCA	OS	Quartile	II,III,IV	0.734	0.529	.002	68	view →
OV	OS	Tertile	All	0.757	0.613	.001	52	view →
LGG	DFS	Median	All	0.775	0.884	<.001	50	view →
READ	OS	Median	II,III,IV	0.755	0.416	.002	29	view →
STAD	DFS	Quartile	IV	0.123	0.597	.003	27	view →
PAAD	OS	Tertile	All	0.608	0.331	.011	18	view →
PRAD	DFS	Median	All	0.829	0.934	<.001	18	view →
LUAD	OS	Tertile	II,III,IV	0.408	0.131	.002	18	view →
GBM	DFS	Tertile	All	0.146	0.282	.001	16	view →
COAD	DFS	Quartile	III,IV	0.848	0.540	.004	15	view →
UVM	DFS	Median	All	0.303	0.658	.019	13	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

EXTL3-AS1–KIRC (OS)

Open the KIRC breakdown →