EXOSC6

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, EXOSC6 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. BLCA shows the largest number of these associations.

The most reproducible EXOSC6-associated genes across cancer lineages are KYNUP1 and RN7SL242P. Each is linked with EXOSC6 in more than 1 cancer types. Because this analysis shows association rather than direction, both EXOSC6-to-partner and partner-to-EXOSC6 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EXOSC6→partner) and Y-score (partner→EXOSC6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLCAKYNUP1 →+0.039+6.618<.001.00131
BLCARN7SL242P →+0.236+5.329<.001.00631
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

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