EXOC5

Across TCGA patient cohorts, EXOC5 mutation is significantly associated with the RNA expression of many other genes, with 5,178 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EXOC5-associated genes across cancer lineages are RN7SL658P, MIR98, and RNU6-42P. Each is linked with EXOC5 in more than 1 cancer types. Because this analysis shows association rather than direction, both EXOC5-to-partner and partner-to-EXOC5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL658P grouped by EXOC5-low versus EXOC5-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EXOC5→partner) and Y-score (partner→EXOC5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RN7SL658P →	+0.178	+6.144	<.001	.001	3	2
UCEC	MIR98 →	+0.168	+1.702	.001	.007	3	2
UCEC	RNU6-42P →	+0.415	+1.626	.003	.001	3	2
UCEC	RNU6-22P →	+0.188	+1.714	<.001	.003	3	2
UCEC	TRAJ58 →	+0.239	+1.630	.002	.006	3	2
UCEC	TRAJ21 →	+0.344	+1.918	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,178 associations by consensus.

RN7SL658P by EXOC5 expression — CESC

Explore this box plot interactively →