EXOC1L

Across TCGA patient cohorts, EXOC1L mutation is significantly associated with the RNA expression of many other genes, with 17 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EXOC1L-associated genes across cancer lineages are RN7SL134P, RN7SL230P, and RPS29P32. Each is linked with EXOC1L in more than 1 cancer types. Because this analysis shows association rather than direction, both EXOC1L-to-partner and partner-to-EXOC1L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL134P grouped by EXOC1L-low versus EXOC1L-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EXOC1L→partner) and Y-score (partner→EXOC1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL134P →	+0.247	+4.184	<.001	.003	3	1
UCEC	RN7SL230P →	+0.552	+3.911	<.001	.007	3	1
UCEC	RPS29P32 →	+1.226	+4.184	<.001	.003	3	1
UCEC	RN7SKP45 →	+0.280	+4.750	<.001	.005	3	1
UCEC	RNU6-340P →	+0.352	+4.442	<.001	.007	3	1
UCEC	RNY1P1 →	+0.539	+4.750	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

RN7SL134P by EXOC1L expression — UCEC

Explore this box plot interactively →