EXOC1L

Across TCGA pan-cancer cohorts, EXOC1L RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated EXOC1L data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher EXOC1L RNA is associated with worse overall survival. In most high-consensus cancer types, elevated EXOC1L expression acts as an unfavorable survival marker, although some lineages such as READ and PCPG show a favorable association.

ACC, THYM, and BRCA are the cancer types where EXOC1L RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	OS	Tertile	All	0.248	0.719	<.001	75	view →
THYM	OS	Tertile	All	0.623	0.942	<.001	56	view →
BRCA	DFS	Tertile	All	0.140	1.000	.001	36	view →
KICH	DFS	Tertile	III,IV	0.035	0.772	.021	18	view →
DLBC	OS	Tertile	II,III,IV	0.118	0.802	.025	15	view →
MESO	OS	Tertile	II,III,IV	0.262	0.711	.019	15	view →
PAAD	OS	Median	All	0.513	0.668	.004	13	view →
KIRP	OS	Tertile	All	0.361	0.727	.033	9	view →
THCA	OS	Tertile	III,IV	0.843	0.984	.045	9	view →
READ	OS	Median	IV	1.000	0.677	.008	9	view →
KIRC	DFS	Tertile	III,IV	0.541	0.674	.046	6	view →
GBM	DFS	Median	All	0.196	0.355	.017	3	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

EXOC1L–ACC (OS)

Open the ACC breakdown →