ETV2

Across TCGA patient cohorts, ETV2 protein abundance is significantly associated with the RNA expression of many other genes, with 10,045 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ETV2-associated genes across cancer lineages are ARHGAP5, SC5D, and CILK1. Each is linked with ETV2 in more than 3 cancer types. Because this analysis shows association rather than direction, both ETV2-to-partner and partner-to-ETV2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ETV2 versus ARHGAP5 in GBM, with a Pearson correlation of -0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ETV2→partner) and Y-score (partner→ETV2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ARHGAP5 →	-0.623	-0.504	<.001	<.001	3	4
LSCC	SC5D →	-0.708	-0.385	<.001	.003	3	4
LSCC	CILK1 →	-0.778	-0.440	<.001	<.001	3	4
LSCC	SAMD12 →	-1.230	-0.559	<.001	<.001	3	4
GBM	PKP4-AS1 →	-0.462	-0.300	<.001	.001	3	4
LSCC	SAP18 →	-0.548	-0.466	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,045 associations by consensus.

ETV2 vs ARHGAP5 — GBM

Explore this scatter interactively →