ETS1

Across TCGA patient cohorts, ETS1 mutation is significantly associated with the RNA expression of many other genes, with 4,810 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ETS1-associated genes across cancer lineages are MIR8064, ZFP91-CNTF, and RNU6-162P. Each is linked with ETS1 in more than 2 cancer types. Because this analysis shows association rather than direction, both ETS1-to-partner and partner-to-ETS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR8064 grouped by ETS1-low versus ETS1-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ETS1→partner) and Y-score (partner→ETS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MIR8064 →	+0.582	+3.283	.001	.001	3	3
UCEC	ZFP91-CNTF →	+0.018	+1.300	<.001	.005	3	3
STAD	RNU6-162P →	+0.352	+5.274	.008	.006	3	3
UCEC	RN7SL248P →	+0.033	+2.296	.001	.007	3	2
UCEC	CRYBB2P1 →	+0.283	+1.408	.008	.001	3	2
UCEC	TXN2 →	+0.336	+2.174	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,810 associations by consensus.

MIR8064 by ETS1 expression — BRCA

Explore this box plot interactively →