ETNPPL

Across TCGA patient cohorts, ETNPPL mutation is significantly associated with the RNA expression of many other genes, with 2,834 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ETNPPL-associated genes across cancer lineages are MIR8053, MRPS15P1, and MIR7159. Each is linked with ETNPPL in more than 2 cancer types. Because this analysis shows association rather than direction, both ETNPPL-to-partner and partner-to-ETNPPL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR8053 grouped by ETNPPL-low versus ETNPPL-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ETNPPL→partner) and Y-score (partner→ETNPPL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	MIR8053 →	+0.277	+4.399	<.001	.006	3	3
BLCA	MRPS15P1 →	+0.091	+4.238	.002	.008	3	3
BRCA	MIR7159 →	+0.703	+5.317	<.001	.006	3	2
HNSC	ZPBP →	+0.063	+3.930	.001	.004	3	2
CESC	LINC02559 →	+1.780	+6.342	<.001	.001	3	2
UCEC	RNA5SP412 →	+0.484	+2.552	.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,834 associations by consensus.

MIR8053 by ETNPPL expression — COAD

Explore this box plot interactively →