ETNPPL

Across TCGA cell cohorts, ETNPPL mutation is significantly associated with the mutation status of many other genes, with 2,527 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ETNPPL-associated genes across cancer lineages are DCAF12, ACACA, and BRD3. Each is linked with ETNPPL in more than 2 cancer types. Because this analysis shows association rather than direction, both ETNPPL-to-partner and partner-to-ETNPPL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DCAF12 grouped by ETNPPL-low versus ETNPPL-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ETNPPL→partner) and Y-score (partner→ETNPPL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	DCAF12 →	+4.584	+4.584	.007	.007	1	3
BLOOD_Leukemia	ACACA →	+4.309	+4.560	.007	.007	1	3
LUNG_SCLC	BRD3 →	+4.502	+5.066	.007	.007	1	3
BLOOD_Lymphoma	CHRD →	+5.584	+5.014	.003	.003	1	3
BLOOD_Lymphoma	RFFL →	+5.584	+5.014	.003	.003	1	3
BLOOD_Leukemia	ANXA9 →	+4.894	+4.894	.004	.004	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,527 associations by consensus.

DCAF12 by ETNPPL expression — BLOOD_Lymphoma

Explore this box plot interactively →