ETF1

Across TCGA cell cohorts, ETF1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,813 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ETF1-associated GO terms across cancer lineages are Positive regulation of rRNA processing, Maturation of SSU-rRNA, and Regulation of sister chromatid segregation. Each is linked with ETF1 in more than 16 cancer types. Because this analysis shows association rather than direction, both ETF1-to-partner and partner-to-ETF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of rRNA processing grouped by ETF1-low versus ETF1-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ETF1→partner) and Y-score (partner→ETF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Positive regulation of rRNA processing →	+0.167	+0.942	.001	<.001	3	17
OESOPHAGUS	Maturation of SSU-rRNA →	+0.122	+0.758	.004	.001	3	16
URINARY_TRACT	Regulation of sister chromatid segregation →	+0.106	+0.616	<.001	.003	3	16
LIVER	Regulation of chromosome segregation →	+0.116	+0.721	.007	.008	3	15
PANCREAS	Double-strand break repair via nonhomologous end joining →	+0.061	+0.814	<.001	.003	3	15
PANCREAS	DNA replication initiation →	+0.179	+0.909	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,813 associations by consensus.

Positive regulation of rRNA processing by ETF1 expression — OESOPHAGUS

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