ETF1

Across TCGA pan-cancer cohorts, ETF1 RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated ETF1 data layer compared with 10 for mutation status and 6 for mass-spec protein.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher ETF1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated ETF1 expression acts as an unfavorable survival marker, although some lineages such as KIRC and READ show a favorable association.

HNSC, KIRC, and ACC are the cancer types where ETF1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Quartile	All	0.237	0.593	.001	77	view →
KIRC	OS	Quartile	All	0.693	0.524	.002	54	view →
ACC	DFS	Median	All	0.270	0.617	.005	53	view →
READ	DFS	Median	All	0.878	0.360	<.001	52	view →
LIHC	OS	Median	All	0.427	0.587	<.001	49	view →
KIRP	DFS	Median	All	0.867	0.949	.002	48	view →
LGG	OS	Median	All	0.752	0.873	<.001	37	view →
UVM	DFS	Quartile	III,IV	0.095	1.000	.006	35	view →
KICH	DFS	Median	II,III,IV	0.564	0.920	.004	34	view →
COAD	OS	Tertile	All	0.945	0.800	.006	27	view →
SCLC	DFS	Median	All	0.281	0.578	.002	25	view →
BLCA	DFS	Quartile	All	0.202	0.577	.010	23	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 25 lineages.

ETF1–HNSC (OS)

Open the HNSC breakdown →