ETF1

Across TCGA pan-cancer cohorts, ETF1 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of ETF1’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where ETF1 RNA is repressed in tumor relative to normal tissue. In most cancer types ETF1 is over-expressed in tumor, although a few such as LUAD and THCA show the opposite, repressed pattern.

LUAD, LIHC, and THCA are the cancer types where ETF1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ETF1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	Female	II,III,IV	−0.622	<.001	10	view →
LIHC	Male	II,III,IV	+0.899	<.001	9	view →
THCA	Female	All	−0.477	<.001	6	view →
BLCA	All	All	−0.431	.003	6	view →
KICH	All	All	−0.918	<.001	5	view →
COAD	All	II,III,IV	+0.347	.003	5	view →
READ	All	III,IV	+0.780	.004	4	view →
CHOL	All	All	+1.575	<.001	3	view →
LUSC	All	All	−0.236	.009	3	view →
BRCA	All	IV	−0.570	.015	2	view →
KIRP	Male	All	−0.314	.028	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

ETF1–LUAD

Open the LUAD breakdown →