ESPL1

Across TCGA patient cohorts, ESPL1 protein abundance is significantly associated with the RNA expression of many other genes, with 1,597 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ESPL1-associated genes across cancer lineages are NUP107, CENPA, and CDC20. Each is linked with ESPL1 in more than 2 cancer types. Because this analysis shows association rather than direction, both ESPL1-to-partner and partner-to-ESPL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ESPL1 versus NUP107 in UCEC, with a Pearson correlation of 0.56.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ESPL1→partner) and Y-score (partner→ESPL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	NUP107 →	+0.888	+0.506	.007	.005	3	2
LUAD	CENPA →	+2.087	+1.337	.006	.008	3	2
UCEC	CDC20 →	+2.359	+0.561	.001	<.001	3	2
UCEC	POLR1B →	+0.653	+0.571	.006	.002	3	2
LUAD	PKMYT1 →	+1.640	+1.080	.002	.004	3	2
UCEC	CCNB1 →	+1.493	+0.628	.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,597 associations by consensus.

ESPL1 vs NUP107 — UCEC

Explore this scatter interactively →