ERVV-1

Across TCGA patient cohorts, ERVV-1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,796 significant associations in total. STAD shows the largest number of these associations.

The most reproducible ERVV-1-associated GO terms across cancer lineages are Establishment or maintenance of bipolar cell polarity, Pore complex assembly, and Cell-cell junction organization. Each is linked with ERVV-1 in more than 9 cancer types. Because this analysis shows association rather than direction, both ERVV-1-to-partner and partner-to-ERVV-1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Establishment or maintenance of bipolar cell polarity grouped by ERVV-1-low versus ERVV-1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ERVV-1→partner) and Y-score (partner→ERVV-1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Establishment or maintenance of bipolar cell polarity →	+0.047	+0.194	<.001	<.001	3	10
STAD	Pore complex assembly →	+0.066	+0.188	<.001	<.001	3	10
STAD	Cell-cell junction organization →	+0.043	+0.178	<.001	<.001	3	10
STAD	Hepatocyte apoptotic process →	+0.054	+0.168	<.001	<.001	3	9
SCLC	Pyrimidine nucleoside triphosphate metabolic process →	+0.108	+0.182	<.001	<.001	3	9
STAD	Obsolete mRNA polyadenylation →	+0.054	+0.184	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,796 associations by consensus.

Establishment or maintenance of bipolar cell polarity by ERVV-1 expression — STAD

Explore this box plot interactively →