ERVV-1

Across TCGA cell cohorts, ERVV-1 RNA expression is significantly associated with the go_rna of many other GO terms, with 358 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible ERVV-1-associated GO terms across cancer lineages are Positive regulation of intracellular transport, Ribonucleoside diphosphate metabolic process, and Positive regulation of intracellular protein transport. Each is linked with ERVV-1 in more than 5 cancer types. Because this analysis shows association rather than direction, both ERVV-1-to-partner and partner-to-ERVV-1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of intracellular transport grouped by ERVV-1-low versus ERVV-1-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ERVV-1→partner) and Y-score (partner→ERVV-1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Positive regulation of intracellular transport →	+0.050	+0.025	<.001	.007	3	6
PANCREAS	Ribonucleoside diphosphate metabolic process →	+0.066	+0.027	<.001	.004	3	4
PANCREAS	Positive regulation of intracellular protein transport →	+0.073	+0.026	<.001	.008	2	5
SOFT_TISSUE	Regulation of intracellular transport →	+0.042	+0.026	.001	.003	3	4
SOFT_TISSUE	Hemidesmosome assembly →	+0.147	+0.023	.003	.008	3	3
URINARY_TRACT	Striated muscle contraction →	+0.040	+0.563	.003	.007	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 358 associations by consensus.

Positive regulation of intracellular transport by ERVV-1 expression — SOFT_TISSUE

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