ERVH48-1

Across TCGA patient cohorts, ERVH48-1 mutation is significantly associated with the total protein of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ERVH48-1-associated genes across cancer lineages are Ku80 and Cyclin-E2. Each is linked with ERVH48-1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ERVH48-1-to-partner and partner-to-ERVH48-1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ku80 grouped by ERVH48-1-low versus ERVH48-1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ERVH48-1→partner) and Y-score (partner→ERVH48-1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Ku80 →	+0.352	+2.820	.015	.036	3	1
UCEC	Cyclin-E2 →	+0.227	+2.817	.027	.036	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Ku80 by ERVH48-1 expression — UCEC

Explore this box plot interactively →