ERVFRD-3

Across TCGA patient cohorts, ERVFRD-3 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,075 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible ERVFRD-3-associated GO terms across cancer lineages are Golgi organization, Nuclear-transcribed mRNA catabolic process, and Positive regulation of chromosome organization. Each is linked with ERVFRD-3 in more than 31 cancer types. Because this analysis shows association rather than direction, both ERVFRD-3-to-partner and partner-to-ERVFRD-3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Golgi organization grouped by ERVFRD-3-low versus ERVFRD-3-high in DLBC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ERVFRD-3→partner) and Y-score (partner→ERVFRD-3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
DLBC	Golgi organization →	+0.058	+0.124	<.001	<.001	3	32
DLBC	Nuclear-transcribed mRNA catabolic process →	+0.065	+0.123	<.001	<.001	3	32
LAML	Positive regulation of chromosome organization →	+0.064	+0.817	<.001	<.001	3	31
CHOL	Nuclear-transcribed mRNA catabolic process, nonsense-mediated decay →	+0.082	+0.234	<.001	<.001	3	31
DLBC	Regulation of cilium assembly →	+0.059	+0.113	<.001	<.001	3	31
THYM	Negative regulation of telomere capping →	+0.076	+0.122	<.001	<.001	3	31

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,075 associations by consensus.

Golgi organization by ERVFRD-3 expression — DLBC

Explore this box plot interactively →