ERICH3

Across TCGA patient cohorts, ERICH3 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,156 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ERICH3-associated proteins across cancer lineages are RPGR_S961, SPA17, and SPATA18_S276. Each is linked with ERICH3 in more than 4 cancer types. Because this analysis shows association rather than direction, both ERICH3-to-partner and partner-to-ERICH3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ERICH3 versus RPGR_S961 in UCEC, with a Pearson correlation of 0.44.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ERICH3→partner) and Y-score (partner→ERICH3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RPGR_S961 →	+0.625	+1.536	<.001	<.001	3	5
GBM	SPA17 →	+0.999	+1.193	.001	.002	3	5
BRCA	SPATA18_S276 →	+2.082	+1.676	<.001	<.001	3	5
UCEC	BBS4 →	+0.458	+1.751	<.001	<.001	3	5
UCEC	TPPP3 →	+1.577	+1.936	<.001	<.001	3	5
GBM	ZMYND10 →	+1.160	+1.086	<.001	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,156 associations by consensus.

ERICH3 vs RPGR_S961 — UCEC

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