ERICH3

Across TCGA cell cohorts, ERICH3 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,029 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible ERICH3-associated GO terms across cancer lineages are Cardiac muscle cell action potential involved in contraction, CD8-positive, alpha-beta T cell differentiation, and CD8-positive, alpha-beta T cell homeostasis. Each is linked with ERICH3 in more than 4 cancer types. Because this analysis shows association rather than direction, both ERICH3-to-partner and partner-to-ERICH3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cardiac muscle cell action potential involved in contraction grouped by ERICH3-low versus ERICH3-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ERICH3→partner) and Y-score (partner→ERICH3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Cardiac muscle cell action potential involved in contraction →	-0.122	-0.141	<.001	<.001	3	5
SKIN	CD8-positive, alpha-beta T cell differentiation →	+0.066	+0.057	<.001	.008	3	5
LUNG_NSCLC_LUAD	CD8-positive, alpha-beta T cell homeostasis →	+0.099	+0.026	<.001	<.001	2	5
KIDNEY	Action potential →	-0.050	-0.134	<.001	<.001	3	4
SKIN	Heart contraction →	-0.087	-0.062	.002	.001	3	4
LUNG_NSCLC_LUAD	Regulation of cell cycle G1/S phase transition →	+0.045	+0.032	.004	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,029 associations by consensus.

Cardiac muscle cell action potential involved in contraction by ERICH3 expression — KIDNEY

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