Across TCGA patient cohorts, ERICH2 mutation is significantly associated with the RNA expression of many other genes, with 15 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ERICH2-associated genes across cancer lineages are IGKV2OR2-10, CHEK2P5, and OR5B19P. Each is linked with ERICH2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ERICH2-to-partner and partner-to-ERICH2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ERICH2→partner) and Y-score (partner→ERICH2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	IGKV2OR2-10 →	+0.135	+4.352	.005	.008	3	1
COAD	CHEK2P5 →	+0.349	+6.003	<.001	.002	3	1
COAD	OR5B19P →	+0.171	+6.721	<.001	<.001	3	1
UCEC	RPL14P6 →	+0.310	+3.847	.001	.008	3	1
UCEC	RNU6-446P →	+0.521	+3.778	.008	.007	3	1
UCEC	RNA5SP338 →	+1.730	+4.223	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

Exploration

ERICH2 survival (RNA) · tumor vs normal (RNA) · all ERICH2 data types