Across TCGA patient cohorts, ERCC6L RNA expression is significantly associated with the protein abundance of many other proteins, with 21,914 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ERCC6L-associated proteins across cancer lineages are TOP2A_S1106, KIF11_T926, and MCM4. Each is linked with ERCC6L in more than 9 cancer types. Because this analysis shows association rather than direction, both ERCC6L-to-partner and partner-to-ERCC6L results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ERCC6L→partner) and Y-score (partner→ERCC6L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	TOP2A_S1106 →	+1.188	+0.777	<.001	<.001	3	10
LUAD	KIF11_T926 →	+0.941	+0.678	<.001	<.001	3	10
LUAD	MCM4 →	+0.788	+0.732	<.001	<.001	3	10
BRCA	SMC4 →	+0.613	+0.799	<.001	<.001	3	10
LUAD	ECT2_T359 →	+1.331	+0.735	<.001	<.001	3	10
LUAD	TOP2A →	+1.037	+0.805	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,914 associations by consensus.

Exploration

ERCC6L survival (RNA) · tumor vs normal (RNA) · all ERCC6L data types