Across TCGA patient cohorts, ERCC6L mutation is significantly associated with the RNA expression of many other genes, with 2,995 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ERCC6L-associated genes across cancer lineages are ANAPC1P3, MED28P8, and TRGJP2. Each is linked with ERCC6L in more than 3 cancer types. Because this analysis shows association rather than direction, both ERCC6L-to-partner and partner-to-ERCC6L results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ERCC6L→partner) and Y-score (partner→ERCC6L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
READ	ANAPC1P3 →	+0.124	+3.469	.001	.007	3	4
CESC	MED28P8 →	+0.125	+3.542	<.001	.007	3	4
STAD	TRGJP2 →	+0.794	+3.512	.004	.007	3	3
SKCM	MIR4661 →	+0.126	+4.640	<.001	.003	3	3
SKCM	OR51B3P →	+0.048	+2.770	<.001	.006	3	3
UCEC	RN7SKP214 →	+0.120	+1.441	.006	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,995 associations by consensus.

Exploration

ERCC6L survival (RNA) · tumor vs normal (RNA) · all ERCC6L data types