EPHX3

Across TCGA patient cohorts, EPHX3 protein abundance is significantly associated with the protein abundance of many other proteins, with 17,240 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible EPHX3-associated proteins across cancer lineages are LMBRD1_S528, ARHGAP24_S369, and ACAP3_S544. Each is linked with EPHX3 in more than 1 cancer types. Because this analysis shows association rather than direction, both EPHX3-to-partner and partner-to-EPHX3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EPHX3 versus LMBRD1_S528 in LSCC, with a Pearson correlation of -0.72.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EPHX3→partner) and Y-score (partner→EPHX3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	LMBRD1_S528 →	-0.803	-2.141	<.001	.005	3	2
LUAD	ARHGAP24_S369 →	-1.195	-0.852	.001	<.001	3	1
LUAD	ACAP3_S544 →	+0.663	+1.761	.002	<.001	3	1
LSCC	ASXL2_S845 →	-0.714	-1.421	.002	.001	3	1
LSCC	ATF2_S62 →	+0.733	+1.484	<.001	<.001	3	1
LSCC	BIRC6_S480 →	-0.400	-1.399	.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,240 associations by consensus.

EPHX3 vs LMBRD1_S528 — LSCC

Explore this scatter interactively →