EPHA8

Across TCGA patient cohorts, EPHA8 protein abundance is significantly associated with the RNA expression of many other genes, with 482 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible EPHA8-associated genes across cancer lineages are MFNG, APOL4, and TLR8. Each is linked with EPHA8 in more than 1 cancer types. Because this analysis shows association rather than direction, both EPHA8-to-partner and partner-to-EPHA8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EPHA8 versus MFNG in LUAD, with a Pearson correlation of -0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EPHA8→partner) and Y-score (partner→EPHA8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	MFNG →	-0.470	-1.031	<.001	.001	3	1
LUAD	APOL4 →	-0.770	-1.404	.001	.001	3	1
LUAD	TLR8 →	-1.007	-1.350	.002	.003	3	1
LUAD	PHEX →	-0.597	-1.069	<.001	<.001	3	1
LUAD	NPRL3 →	+0.525	+0.939	.003	.006	3	1
LUAD	SGTA →	+0.282	+0.953	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 482 associations by consensus.

EPHA8 vs MFNG — LUAD

Explore this scatter interactively →