EPCAM-DT

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, EPCAM-DT RNA expression is significantly associated with the protein abundance of many other proteins, with 12,973 significant associations in total. GBM shows the largest number of these associations.

The most reproducible EPCAM-DT-associated proteins across cancer lineages are ADNP, DOK3, and MACROH2A2. Each is linked with EPCAM-DT in more than 5 cancer types. Because this analysis shows association rather than direction, both EPCAM-DT-to-partner and partner-to-EPCAM-DT results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EPCAM-DT versus ADNP in GBM, with a Pearson correlation of 0.44.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EPCAM-DT→partner) and Y-score (partner→EPCAM-DT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMADNP →+0.298+0.537<.001<.00136
GBMDOK3 →-0.539-0.623<.001.00136
OVMACROH2A2 →+0.739+1.150<.001<.00135
HNSCMYEF2 →+1.255+0.745<.001.00135
CCRCCCD44_S697 →-0.725-0.775<.001<.00135
HNSCCLDN3 →+0.962+0.605<.001<.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 12,973 associations by consensus.

EPCAM-DT vs ADNP — GBM

Per-sample scatter of EPCAM-DT vs ADNP in GBM (Pearson r = 0.44).

Explore this scatter interactively →

Exploration