EPC2

Across TCGA patient cohorts, EPC2 mutation is significantly associated with the RNA expression of many other genes, with 5,120 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EPC2-associated genes across cancer lineages are RNU6-1207P, LINC02598, and ZNF670. Each is linked with EPC2 in more than 2 cancer types. Because this analysis shows association rather than direction, both EPC2-to-partner and partner-to-EPC2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1207P grouped by EPC2-low versus EPC2-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EPC2→partner) and Y-score (partner→EPC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RNU6-1207P →	+0.361	+6.444	<.001	.001	3	3
READ	LINC02598 →	+0.161	+3.203	<.001	.009	3	3
UCEC	ZNF670 →	+0.441	+2.752	.007	.002	3	2
BLCA	MIR30E →	+0.332	+5.588	<.001	.004	3	2
BLCA	RNY4P27 →	+0.523	+6.814	<.001	<.001	3	2
UCEC	EZH2P1 →	+0.245	+1.356	.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,120 associations by consensus.

RNU6-1207P by EPC2 expression — BLCA

Explore this box plot interactively →