EPB42

Across TCGA cell cohorts, EPB42 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,695 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible EPB42-associated GO terms across cancer lineages are Intracellular triglyceride homeostasis, DNA methylation-dependent constitutive heterochromatin formation, and Limb joint morphogenesis. Each is linked with EPB42 in more than 3 cancer types. Because this analysis shows association rather than direction, both EPB42-to-partner and partner-to-EPB42 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Intracellular triglyceride homeostasis grouped by EPB42-low versus EPB42-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EPB42→partner) and Y-score (partner→EPB42) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Intracellular triglyceride homeostasis →	-0.121	-0.025	.001	.004	3	4
BLOOD_Leukemia	DNA methylation-dependent constitutive heterochromatin formation →	-0.083	-1.280	<.001	<.001	3	4
LUNG_NSCLC_LUSC	Limb joint morphogenesis →	+0.177	+0.018	.003	.005	3	3
BLOOD_Lymphoma	Transposable element silencing by heterochromatin formation →	-0.080	-0.026	.003	.006	3	3
BLOOD_Leukemia	Positive regulation of nitric oxide biosynthetic process →	+0.074	+1.308	<.001	<.001	3	3
BLOOD_Lymphoma	Succinate metabolic process →	-0.087	-0.020	.001	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,695 associations by consensus.

Intracellular triglyceride homeostasis by EPB42 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →