EPB41L4B

Across TCGA cell cohorts, EPB41L4B mutation is significantly associated with the RNA expression of many other genes, with 20 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible EPB41L4B-associated genes across cancer lineages are KRT71, CST9, and CYLC1. Each is linked with EPB41L4B in more than 1 cancer types. Because this analysis shows association rather than direction, both EPB41L4B-to-partner and partner-to-EPB41L4B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KRT71 grouped by EPB41L4B-low versus EPB41L4B-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EPB41L4B→partner) and Y-score (partner→EPB41L4B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	KRT71 →	+0.013	+5.643	<.001	.002	3	1
BLOOD_Lymphoma	CST9 →	+0.060	+5.209	<.001	.005	3	1
BLOOD_Lymphoma	CYLC1 →	+0.029	+4.867	<.001	.009	3	1
BLOOD_Lymphoma	KRTAP4-1 →	+0.162	+4.867	<.001	.009	3	1
BLOOD_Lymphoma	C18orf63 →	+0.012	+4.867	<.001	.009	3	1
SOFT_TISSUE	IFNA8 →	+0.052	+4.930	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 20 associations by consensus.

KRT71 by EPB41L4B expression — BLOOD_Lymphoma

Explore this box plot interactively →