Across TCGA patient cohorts, EOLA2 mutation is significantly associated with the RNA expression of many other genes, with 908 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EOLA2-associated genes across cancer lineages are RN7SL248P, NUDT19P2, and RN7SL303P. Each is linked with EOLA2 in more than 1 cancer types. Because this analysis shows association rather than direction, both EOLA2-to-partner and partner-to-EOLA2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EOLA2→partner) and Y-score (partner→EOLA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL248P →	+0.084	+3.606	<.001	.002	3	2
COAD	NUDT19P2 →	+0.387	+6.251	<.001	.001	3	2
COAD	RN7SL303P →	+0.655	+5.602	<.001	.004	3	2
BRCA	DKKL1P1 →	+0.067	+5.646	<.001	.004	3	2
UCEC	HSPD1P18 →	+0.195	+2.281	<.001	.007	3	2
UCEC	LINC01607 →	-0.715	-3.443	.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 908 associations by consensus.

Exploration

EOLA2 survival (RNA) · tumor vs normal (RNA) · all EOLA2 data types