ENPP6

Across TCGA patient cohorts, ENPP6 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,989 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible ENPP6-associated proteins across cancer lineages are SYNPO2_S363, ZAP70, and ARID5A_S463. Each is linked with ENPP6 in more than 4 cancer types. Because this analysis shows association rather than direction, both ENPP6-to-partner and partner-to-ENPP6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ENPP6 versus SYNPO2_S363 in LUAD, with a Pearson correlation of 0.46.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ENPP6→partner) and Y-score (partner→ENPP6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	SYNPO2_S363 →	+0.974	+0.279	<.001	<.001	3	5
BRCA	ZAP70 →	+0.621	+0.605	<.001	<.001	3	4
LSCC	ARID5A_S463 →	+0.787	+0.556	<.001	<.001	3	4
LSCC	CD3G →	+0.574	+0.499	<.001	<.001	3	4
LSCC	CELF2 →	+0.615	+0.532	<.001	<.001	3	4
BRCA	CLIC2 →	+0.523	+0.410	<.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,989 associations by consensus.

ENPP6 vs SYNPO2_S363 — LUAD

Explore this scatter interactively →