ENOX1

Across TCGA cell cohorts, ENOX1 mutation is significantly associated with the RNA expression of many other genes, with 64 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ENOX1-associated genes across cancer lineages are LUZP4, KRTAP2-1, and H4C6. Each is linked with ENOX1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ENOX1-to-partner and partner-to-ENOX1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LUZP4 grouped by ENOX1-low versus ENOX1-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ENOX1→partner) and Y-score (partner→ENOX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	LUZP4 →	+0.039	+3.215	<.001	.007	3	1
LUNG_NSCLC_LUAD	KRTAP2-1 →	+0.119	+4.188	<.001	.001	3	1
LUNG_NSCLC_LUAD	H4C6 →	+0.199	+3.628	.001	.002	3	1
LUNG_NSCLC_LUAD	CCL18 →	+0.032	+3.628	<.001	.002	3	1
SKIN	KRTAP5-4 →	+0.101	+4.977	<.001	.007	3	1
LARGE_INTESTINE	TSPAN12 →	+1.331	+3.212	.002	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 64 associations by consensus.

LUZP4 by ENOX1 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →