ENO1

Across TCGA patient cohorts, ENO1 RNA expression is significantly associated with the protein abundance of many other proteins, with 19,625 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ENO1-associated proteins across cancer lineages are RRM2, WDHD1, and HMGN4. Each is linked with ENO1 in more than 8 cancer types. Because this analysis shows association rather than direction, both ENO1-to-partner and partner-to-ENO1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ENO1 versus RRM2 in UCEC, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ENO1→partner) and Y-score (partner→ENO1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RRM2 →	+0.849	+1.562	<.001	<.001	3	9
LSCC	WDHD1 →	+0.797	+0.782	<.001	<.001	3	8
BRCA	HMGN4 →	-0.874	-0.919	<.001	<.001	3	8
BRCA	SMC4 →	+0.661	+0.961	<.001	<.001	3	8
UCEC	NCAPH →	+0.842	+1.448	<.001	<.001	3	8
OV	NCAPG_S674 →	+1.058	+0.592	<.001	.007	2	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,625 associations by consensus.

ENO1 vs RRM2 — UCEC

Explore this scatter interactively →