ENKUR

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ENKUR protein abundance is significantly associated with the RNA expression of many other genes, with 2,819 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ENKUR-associated genes across cancer lineages are CCDC114, CDHR3, and TTLL9. Each is linked with ENKUR in more than 2 cancer types. Because this analysis shows association rather than direction, both ENKUR-to-partner and partner-to-ENKUR results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ENKUR versus CCDC114 in UCEC, with a Pearson correlation of 0.55.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ENKUR→partner) and Y-score (partner→ENKUR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECCCDC114 →+1.609+0.919.002.00533
LUADCDHR3 →+1.612+0.744<.001<.00133
UCECTTLL9 →+1.135+0.822<.001<.00133
UCECSTOML3 →+1.722+0.710.002.00333
UCECBRCA2 →-1.290-1.040.001<.00133
UCECDNAI4 →+2.123+1.168<.001.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,819 associations by consensus.

ENKUR vs CCDC114 — UCEC

Per-sample scatter of ENKUR vs CCDC114 in UCEC (Pearson r = 0.55).

Explore this scatter interactively →

Exploration