ENKUR

Across TCGA pan-cancer cohorts, ENKUR RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated ENKUR data layer compared with 1 for mutation status and 1 for mass-spec protein.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher ENKUR RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated ENKUR expression acts as an unfavorable survival marker, although some lineages such as READ and UCEC show a favorable association.

BLCA, SCLC, and KIRP are the cancer types where ENKUR RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	DFS	Tertile	All	0.507	0.747	.002	48	view →
SCLC	OS	Median	All	0.573	0.822	.003	48	view →
KIRP	DFS	Tertile	All	0.772	0.960	<.001	33	view →
READ	DFS	Quartile	IV	0.917	0.376	.012	25	view →
UCEC	OS	Median	All	0.952	0.899	.007	18	view →
HNSC	OS	Median	All	0.723	0.476	<.001	17	view →
STAD	OS	Median	III,IV	0.347	0.625	.018	15	view →
PCPG	DFS	Median	All	1.000	0.701	.004	12	view →
COAD	OS	Quartile	III,IV	0.832	0.543	.011	11	view →
DLBC	DFS	Median	III,IV	1.000	0.525	.013	11	view →
UCS	DFS	Median	III,IV	0.450	0.138	.019	10	view →
UVM	DFS	Tertile	III,IV	0.992	0.498	.010	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

ENKUR–BLCA (DFS)

Open the BLCA breakdown →