ENHO

Across TCGA patient cohorts, ENHO mutation is significantly associated with the RNA expression of many other genes, with 53 significant associations in total. COAD shows the largest number of these associations.

The most reproducible ENHO-associated genes across cancer lineages are SLC25A52, TRHR, and LINC02873. Each is linked with ENHO in more than 1 cancer types. Because this analysis shows association rather than direction, both ENHO-to-partner and partner-to-ENHO results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SLC25A52 grouped by ENHO-low versus ENHO-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ENHO→partner) and Y-score (partner→ENHO) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	SLC25A52 →	+0.136	+3.992	<.001	.003	3	1
COAD	TRHR →	+0.153	+3.515	<.001	.005	3	1
COAD	LINC02873 →	+0.089	+4.021	.008	.003	3	1
COAD	OR5F2P →	+0.147	+5.734	<.001	<.001	3	1
COAD	LINC00319 →	+0.060	+4.257	<.001	.001	3	1
COAD	LINC00477 →	+0.039	+4.212	.007	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 53 associations by consensus.

SLC25A52 by ENHO expression — COAD

Explore this box plot interactively →