ENHO

Across TCGA pan-cancer cohorts, ENHO RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of ENHO’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where ENHO RNA is repressed in tumor relative to normal tissue. In most cancer types ENHO is over-expressed in tumor, although a few such as COAD and KIRC show the opposite, repressed pattern.

COAD, KIRC, and LUAD are the cancer types where ENHO tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ENHO RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Female	III,IV	−2.040	<.001	12	view →
KIRC	Male	IV	−0.939	<.001	11	view →
LUAD	Female	All	−1.192	<.001	7	view →
READ	All	II,III,IV	−2.335	<.001	6	view →
CHOL	Male	All	−2.953	<.001	5	view →
KICH	All	All	−0.691	.017	3	view →
HNSC	Female	III,IV	−0.621	.012	3	view →
PRAD	All	All	−0.597	.017	2	view →
STAD	Male	IV	−1.589	<.001	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

ENHO–COAD

Open the COAD breakdown →