ENDOG

Across TCGA patient cohorts, ENDOG RNA expression is significantly associated with the protein abundance of many other proteins, with 7,953 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ENDOG-associated proteins across cancer lineages are CAP2_S309, FXN, and PRRC2B_S388. Each is linked with ENDOG in more than 3 cancer types. Because this analysis shows association rather than direction, both ENDOG-to-partner and partner-to-ENDOG results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ENDOG versus CAP2_S309 in UCEC, with a Pearson correlation of 0.32.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ENDOG→partner) and Y-score (partner→ENDOG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CAP2_S309 →	+0.576	+0.767	.003	.003	3	3
PDAC	FXN →	+0.403	+0.601	<.001	<.001	3	3
LSCC	PRRC2B_S388 →	+0.374	+0.636	.001	.004	3	3
OV	MDM1_T515 →	+0.744	+0.771	.006	.006	3	3
COAD	C9orf78 →	+0.280	+0.621	.007	.007	2	4
LUAD	MRPL47 →	+0.353	+0.554	.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,953 associations by consensus.

ENDOG vs CAP2_S309 — UCEC

Explore this scatter interactively →