EMX1

Across TCGA cell cohorts, EMX1 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible EMX1-associated genes across cancer lineages are MSGN1, RBMY1J, and SCN10A. Each is linked with EMX1 in more than 1 cancer types. Because this analysis shows association rather than direction, both EMX1-to-partner and partner-to-EMX1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MSGN1 grouped by EMX1-low versus EMX1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EMX1→partner) and Y-score (partner→EMX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	MSGN1 →	+0.056	+3.345	.007	.007	3	1
LARGE_INTESTINE	RBMY1J →	+0.006	+4.022	<.001	.006	3	1
LUNG_NSCLC_LUAD	SCN10A →	+0.006	+5.662	<.001	.002	3	1
LUNG_NSCLC_LUAD	USP17L18 →	+0.006	+4.887	<.001	.009	3	1
LUNG_NSCLC_LUAD	OR8B4 →	+0.034	+4.887	<.001	.009	3	1
LARGE_INTESTINE	APLNR →	+0.289	+3.799	<.001	.003	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

MSGN1 by EMX1 expression — LARGE_INTESTINE

Explore this box plot interactively →