ELP4

Across TCGA patient cohorts, ELP4 mutation is significantly associated with the RNA expression of many other genes, with 566 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ELP4-associated genes across cancer lineages are RNA5SP66, RPS12P15, and MIR4646. Each is linked with ELP4 in more than 2 cancer types. Because this analysis shows association rather than direction, both ELP4-to-partner and partner-to-ELP4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP66 grouped by ELP4-low versus ELP4-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ELP4→partner) and Y-score (partner→ELP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RNA5SP66 →	+0.452	+5.132	<.001	.002	3	3
COAD	RPS12P15 →	+0.168	+4.693	<.001	.007	3	3
KIRP	MIR4646 →	+0.563	+5.376	<.001	.005	3	2
LUAD	MIR7-3 →	+0.257	+4.122	<.001	.009	3	2
LUAD	CUBNP1 →	+0.014	+4.786	<.001	.003	3	2
LUAD	SPRING1P1 →	+0.039	+4.786	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 566 associations by consensus.

RNA5SP66 by ELP4 expression — HNSC

Explore this box plot interactively →