ELP4

Across TCGA pan-cancer cohorts, ELP4 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated ELP4 data layer compared with 6 for mutation status and 4 for mass-spec protein.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher ELP4 RNA is associated with better overall survival. In most high-consensus cancer types, elevated ELP4 expression acts as an unfavorable survival marker, although some lineages such as KIRC and READ show a favorable association.

KIRC, ACC, and MESO are the cancer types where ELP4 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Median	All	0.736	0.524	<.001	105	view →
ACC	DFS	Median	All	0.267	0.620	<.001	88	view →
MESO	OS	Quartile	All	0.390	0.687	<.001	60	view →
HNSC	OS	Median	II,III,IV	0.699	0.785	.004	53	view →
LIHC	OS	Median	All	0.711	0.838	.001	41	view →
READ	OS	Quartile	II,III,IV	1.000	0.281	.004	40	view →
KICH	OS	Median	II,III,IV	0.663	0.958	.009	24	view →
LAML	DFS	Median	All	0.493	0.654	.020	18	view →
BRCA	DFS	Quartile	III,IV	0.516	0.264	.019	13	view →
THCA	DFS	Median	All	0.966	0.902	.001	12	view →
LUAD	DFS	Tertile	IV	0.949	0.298	.013	12	view →
UCS	DFS	Quartile	II,III,IV	0.138	0.658	.021	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

ELP4–KIRC (OS)

Open the KIRC breakdown →