Q-omics provides the consensus-scored CUBNP1 profile across patient tissues and cancer cell-line models. CUBNP1 expression is associated with patient survival in 13 of 34 cancer types, with the highest sampling consensus in BRCA. Among the 18 cancer types available for tumor–normal comparison, CUBNP1 is differentially expressed in 1, with the highest sampling consensus in KIRP. Additionally, CUBNP1 RNA expression shows 6,864 significant gene co-expression associations, with the highest sampling consensus in COAD. Together, these results highlight BRCA, KIRP, and COAD as cancer lineages where CUBNP1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for CUBNP1 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes CUBNP1 survival associations across molecular data types. CUBNP1 RNA expression shows survival associations in the most cancer types (13). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible CUBNP1 RNA expression–survival associations across cancer types. High CUBNP1 expression shows unfavorable associations in BRCA, LGG, PAAD, LIHC and BLCA, but favorable associations in KIRC. The BRCA Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify BRCA as the clearest survival context for CUBNP1 RNA expression.
This table summarizes CUBNP1 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 1. The strongest signals are observed in KIRP for RNA.
This table ranks reproducible tumor–normal expression differences for CUBNP1. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. CUBNP1 shows lower tumor expression in KIRP. The KIRP box plot shows higher CUBNP1 RNA expression in normal versus tumor tissue (log2 FC = −0.037, t-test p = .002).
This table shows molecular features associated with CUBNP1 in patient tissues and cancer cell lines. In patient samples, CUBNP1 shows the broadest associations at the RNA and protein expression levels, with COAD recurring as the lineage with the largest associated feature set.
