ELOVL6

Across TCGA cell cohorts, ELOVL6 mutation is significantly associated with the mutation status of many other genes, with 452 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ELOVL6-associated genes across cancer lineages are METTL25, PJA1, and SCYL3. Each is linked with ELOVL6 in more than 2 cancer types. Because this analysis shows association rather than direction, both ELOVL6-to-partner and partner-to-ELOVL6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, METTL25 grouped by ELOVL6-low versus ELOVL6-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ELOVL6→partner) and Y-score (partner→ELOVL6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	METTL25 →	+5.824	+5.824	.002	.002	1	3
SKIN	PJA1 →	+4.824	+5.392	.004	.004	1	3
SKIN	SCYL3 →	+4.824	+5.392	.004	.004	1	2
SKIN	PMS1 →	+5.824	+5.824	.002	.002	1	2
SKIN	SCARB1 →	+4.824	+5.392	.004	.004	1	2
SKIN	TBX3 →	+5.824	+5.824	.002	.002	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 452 associations by consensus.

METTL25 by ELOVL6 expression — SKIN

Explore this box plot interactively →