ELOVL6

Across TCGA pan-cancer cohorts, ELOVL6 RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of ELOVL6’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where ELOVL6 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types ELOVL6 is over-expressed in tumor, although a few such as COAD and CHOL show the opposite, repressed pattern.

LUAD, BLCA, and COAD are the cancer types where ELOVL6 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ELOVL6 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	Male	II,III,IV	+1.533	<.001	8	view →
BLCA	All	III,IV	+1.245	.002	7	view →
COAD	Female	All	−0.802	<.001	7	view →
THCA	All	All	+0.575	<.001	7	view →
LUSC	Male	All	+1.161	<.001	6	view →
UCEC	All	All	+0.978	<.001	6	view →
KIRP	All	II,III,IV	+0.796	<.001	6	view →
PAAD	All	All	+1.285	.003	4	view →
BRCA	All	II,III,IV	+0.508	<.001	4	view →
CHOL	All	All	−1.627	.001	3	view →
READ	All	All	−1.295	.008	2	view →
KIRC	All	All	−0.314	.017	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

ELOVL6–LUAD

Open the LUAD breakdown →