ELOC

Across TCGA patient cohorts, ELOC mutation is significantly associated with the RNA expression of many other genes, with 24 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ELOC-associated genes across cancer lineages are RNA5SP419, MIR8062, and LINC01727. Each is linked with ELOC in more than 1 cancer types. Because this analysis shows association rather than direction, both ELOC-to-partner and partner-to-ELOC results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP419 grouped by ELOC-low versus ELOC-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ELOC→partner) and Y-score (partner→ELOC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP419 →	+0.949	+4.077	<.001	.001	3	2
BRCA	MIR8062 →	+0.592	+8.471	<.001	.005	3	1
UCEC	LINC01727 →	+0.143	+4.017	<.001	.003	3	1
BRCA	MIR4307 →	+0.355	+7.731	<.001	.009	3	1
LUAD	RNU6-1258P →	+0.443	+7.930	<.001	.008	3	1
UCEC	PPIAL4F →	+0.101	+3.453	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 24 associations by consensus.

RNA5SP419 by ELOC expression — UCEC

Explore this box plot interactively →