ELOA

Across TCGA patient cohorts, ELOA mutation is significantly associated with the RNA expression of many other genes, with 2,709 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ELOA-associated genes across cancer lineages are RN7SL237P, MIR153-2, and RN7SL197P. Each is linked with ELOA in more than 2 cancer types. Because this analysis shows association rather than direction, both ELOA-to-partner and partner-to-ELOA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL237P grouped by ELOA-low versus ELOA-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ELOA→partner) and Y-score (partner→ELOA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RN7SL237P →	+0.540	+5.212	<.001	.007	3	3
COAD	MIR153-2 →	+1.536	+5.212	<.001	.007	3	3
LIHC	RN7SL197P →	+0.158	+5.758	<.001	.003	3	2
UCEC	ANKRD9 →	+0.600	+2.148	<.001	<.001	3	2
UCEC	NDUFAF2 →	+0.602	+2.332	<.001	.003	3	2
UCEC	ZFYVE19 →	+0.458	+2.609	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,709 associations by consensus.

RN7SL237P by ELOA expression — COAD

Explore this box plot interactively →