ELMO3

Across TCGA cell cohorts, ELMO3 mutation is significantly associated with the RNA expression of many other genes, with 68 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ELMO3-associated genes across cancer lineages are CA5A, ITGAD, and SSX7. Each is linked with ELMO3 in more than 1 cancer types. Because this analysis shows association rather than direction, both ELMO3-to-partner and partner-to-ELMO3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CA5A grouped by ELMO3-low versus ELMO3-high in URINARY_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ELMO3→partner) and Y-score (partner→ELMO3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	CA5A →	+0.020	+5.087	<.001	.004	3	1
LARGE_INTESTINE	ITGAD →	+0.012	+3.247	<.001	.001	3	1
STOMACH	SSX7 →	+0.433	+5.285	<.001	.003	3	1
CNS	GPR149 →	+0.016	+4.321	<.001	.009	3	1
CNS	OR11H6 →	+0.026	+4.321	<.001	.009	3	1
BLOOD_Leukemia	GML →	+0.062	+2.982	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 68 associations by consensus.

CA5A by ELMO3 expression — URINARY_TRACT

Explore this box plot interactively →