ELMO3

Across TCGA pan-cancer cohorts, ELMO3 RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of ELMO3’s most consistent transcriptional readouts.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where ELMO3 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types ELMO3 is over-expressed in tumor, although a few such as KICH and KIRP show the opposite, repressed pattern.

BLCA, HNSC, and LUAD are the cancer types where ELMO3 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ELMO3 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BLCA	All	III,IV	+2.179	.003	10	view →
HNSC	Male	All	+0.879	<.001	10	view →
LUAD	All	III,IV	+0.946	<.001	9	view →
THCA	Male	II,III,IV	+0.718	<.001	8	view →
KICH	Male	All	−1.827	<.001	7	view →
LUSC	Male	All	+0.725	<.001	7	view →
KIRP	All	All	−0.861	.003	6	view →
BRCA	All	II,III,IV	+0.660	<.001	6	view →
CHOL	All	All	+3.267	<.001	5	view →
STAD	Male	All	+1.408	.001	5	view →
COAD	All	All	+0.527	<.001	5	view →
KIRC	Male	II,III,IV	−0.785	.006	4	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 14 lineages.

ELMO3–BLCA

Open the BLCA breakdown →