ELF2

Across TCGA patient cohorts, ELF2 mutation is significantly associated with the RNA expression of many other genes, with 3,132 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ELF2-associated genes across cancer lineages are BMS1P11, TUBAP1, and H3P46. Each is linked with ELF2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ELF2-to-partner and partner-to-ELF2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BMS1P11 grouped by ELF2-low versus ELF2-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ELF2→partner) and Y-score (partner→ELF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	BMS1P11 →	+0.072	+3.963	.008	.007	3	2
BRCA	TUBAP1 →	+0.078	+4.331	<.001	.003	3	2
UCEC	H3P46 →	+0.047	+2.877	.005	.007	3	2
UCEC	TUBGCP5 →	+0.398	+2.169	.001	<.001	3	2
SKCM	EXOSC8 →	+0.703	+3.214	.006	.009	3	2
SKCM	GTF3A →	+0.637	+3.227	.006	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,132 associations by consensus.

BMS1P11 by ELF2 expression — BRCA

Explore this box plot interactively →